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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal activates ATXN3. 2 / 2

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"On the other hand, the observation that MG132 blocked SUMO induced degradation of ataxin-3, although the effect was not strong, suggested a role of UPS for this process."

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"Azure C or MG132 that inhibit HSP70 function or proteasome activity can also significantly increase the protein level of Atx3 71Q (XREF_FIG), as in the case of Atx3 22Q (XREF_FIG & XREF_FIG)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...