IndraLab

Statements

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal activates ATXN3. 2 / 2

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"On the other hand, the observation that MG132 blocked SUMO induced degradation of ataxin-3, although the effect was not strong, suggested a role of UPS for this process."

30460066

➶

reach

"Azure C or MG132 that inhibit HSP70 function or proteasome activity can also significantly increase the protein level of Atx3 71Q (XREF_FIG), as in the case of Atx3 22Q (XREF_FIG & XREF_FIG)."

21625540

INDRA sources:

Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal activates ATXN3. 2 / 2

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