IndraLab

Statements

PTGDR activates KCNMA1. 3 / 3
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"Targeting PTGDR reduces basophil accumulation in SLO."
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"Importantly, CXCR4 levels on basophils from pristane treated mice were increased, and PTGDR antagonisms in these mice led as well to prevent basophil accumulation in SLO along with the decrease of CXCR4 expression on basophil surface."
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"In aged and sick Lyn -/- mice, PTGDR antagonists induced reduction of basophil accumulation was associated with a dramatic decrease of CD19 + CD138 + short lived plasma cells in SLO."
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