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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

PTGDR activates KCNMA1. 3 / 3

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"In aged and sick Lyn -/- mice, PTGDR antagonists induced reduction of basophil accumulation was associated with a dramatic decrease of CD19 + CD138 + short lived plasma cells in SLO."

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"Importantly, CXCR4 levels on basophils from pristane treated mice were increased, and PTGDR antagonisms in these mice led as well to prevent basophil accumulation in SLO along with the decrease of CXCR4 expression on basophil surface."

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"Targeting PTGDR reduces basophil accumulation in SLO."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

PTGDR activates KCNMA1. 3 / 3

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