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USP19 activates MGMT. 2 / 2

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"As shown in Figure 1E,F, MGMT stability was dramatically decreased in USP19‐depleted cells, while reconstitution of USP19 could rescue MGMT protein stability in USP19‐depleted cells."

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"To further clarify the effect of USP19‐mediated MGMT stabilization, we assessed whether USP19 deubiquitinated MGMT in cells."

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IndraLab

Statements

USP19 activates MGMT. 2 / 2

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