IndraLab

Statements


| 4 4

reach
"Because Cam1 and Cam2 directly bind the Myo1 IQ motifs (Toya et al., 2001; Sammons et al., 2011) and coimmunoprecipitate with Ank1, their localization was also analyzed."

reach
"The Myo1-Cam1-Cam2 complex bound Ank1, supporting a direct interaction between Myo1 and Ank1 (Figure 2D)."

reach
"Because Cam1 and Cam2 directly bind the Myo1 IQ motifs (Toya et al., 2001; Sammons et al., 2011) and co-immunoprecipitate with Ank1, their localization was also analyzed."

reach
"The Myo1-Cam1-Cam2 complex bound Ank1, supporting a direct interaction between Myo1 and Ank1 (Fig. 2D)."

sparser
"These findings provide evidence that ankyrins and L1CAMs associate in vivo, and furthermore identify the genes and alternatively spliced variants involved in L1 CAMankyrin interactions in premyelinated axons."

sparser
"Recent analysis of structural requirements for L1 CAM binding to ankyrin has demonstrated that the FIGQY tyrosine is essential for ankyrin binding ( xref ; xref )."

sparser
"Our study at two complementary model synapses identifies the regulation of the interaction between the L1-type CAM and Ankyrin as an important novel module enabling local control of synaptic connectivity and function while maintaining general neuronal circuit architecture."

sparser
"Our study identifies the interaction of the L1-type CAM with Ankyrin as a novel regulatory module enabling local and precise control of synaptic connectivity without altering general neuronal circuit architecture."