IndraLab

Statements


OTUD1 binds CARD9 and K33. 2 / 2
| 2

reach
"32 We demonstrate that OTUD1 binds to the CARD9 and removes the K33‐linked ubiquitin from CARD9, thus promoting the assembly of the CBM complex in macrophages upon ISO stimulation."

reach
"We further demonstrated that OTUD1 directly binds to the CARD9 and then removes the K33-linked ubiquitin from CARD9 to promote the assembly of the CARD9-BCL10-MALT1 (CBM) complex, without affecting CARD9 stability."