IndraLab

Statements

KCNMA1 activates PARP1. 3 / 3
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"While SLO is required to activate both during infection, purified SLO activates JNK but not PARP-1."
26838722
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"However, the observation that purified SLO was not sufficient to activate PARP-1 and that SPN was also not required for activation implicates an additional S. pyogenes factor."
25818652
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"To understand the importance of SLO and the activation of PARP, cells were treated with purified SLO to determine if SLO alone is sufficient to induce PARylation."
25818652