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USP18 decreases the amount of cleaved-caspase-3. 3 / 3
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"In contrast, overexpression of USP18 could up-regulated the expression of Bcl-2 and down-regulated the expression of Bax, Cyto-C, and cleaved-caspase-3 in Huh7 and SMMC-7721 cells (Fig. 2d)."
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"Overexpression of USP18 inhibited the expressions of CHOP and cleaved-caspase-3."
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"TM promoted the expression of CHOP and cleaved-caspase-3, which was partly reversed by overexpression of USP18 (Fig. 3c)."
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