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OTUB1 activates endoplasmic reticulum. 2 / 2

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"In addition, Zheng et al. [ 8 ] revealed that OTUB1 promoted cancer cell immunosuppression by preventing ER-associated degradation of immune checkpoint protein PD-L1."

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"Mechanistically, OTUB1 increases ERα in the chromatin-bound fraction, which implies OTUB1 represses ERα motility required for its activity."

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IndraLab

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OTUB1 activates endoplasmic reticulum. 2 / 2

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