IndraLab

Statements

USP7 activates FOXO4. 4 / 4
| 4
reach
"In this respect, the PTEN and FOXO4 tumor suppressors are inactivated by USP7 induced nuclear export (Song et al., 2008; van der Horst et al., 2006)."
22520753
reach
"Our study indicated that MDM2 was up-regulated; this was accompanied with down-regulation of FoxO4, elevation of CyclinD1 and cell proliferation in PASMCs stimulated with PDGF, while knockdown of USP7 attenuated the changes of MDM2, FoxO4 and CyclinD1 as well as PASMCs proliferation caused by PDGF."
34552711
reach
"FOXO4 accumulation in the nucleus may be caused by weak deubiquitination of USP7 downregulation."
33869052
reach
"USP7 mediates PDGF-induced up-regulation of MDM2, down-regulation of FoxO4 and elevation of CyclinD1 in PASMCs."
34552711