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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

COPS5 inhibits DKK1. 3 / 3

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"It is suggested that CSN5 may actively drive abnormal Wnt signals by inhibiting Wnt antagonist Dkk1, thus promoting the development of colorectal cancer."

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"While knockdown of CSN5 increased DKK1 in the supernatant, CSN5 overexpression led to reduced DKK1 secretion."

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"CSN5 and JAB1 suppresses the WNT inhibitor DKK1 in colorectal cancer cells."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

COPS5 inhibits DKK1. 3 / 3

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