IndraLab

Statements


COPS5 inhibits DKK1. 3 / 3
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"It is suggested that CSN5 may actively drive abnormal Wnt signals by inhibiting Wnt antagonist Dkk1, thus promoting the development of colorectal cancer."

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"While knockdown of CSN5 increased DKK1 in the supernatant, CSN5 overexpression led to reduced DKK1 secretion."

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"CSN5 and JAB1 suppresses the WNT inhibitor DKK1 in colorectal cancer cells."