IndraLab

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COPS5 inhibits DKK1. 2 / 2

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"While knockdown of CSN5 increased DKK1 in the supernatant, CSN5 overexpression led to reduced DKK1 secretion."

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"It is suggested that CSN5 may actively drive abnormal Wnt signals by inhibiting Wnt antagonist Dkk1, thus promoting the development of colorectal cancer."

33536782

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Colored badges next to statement headings correspond to evidence counts from knowledge sources, as shown below. Badges to the left of the | separator correspond to curated knowledge base sources, and badges to the right of it correspond to machine reading systems.

IndraLab

Statements

COPS5 inhibits DKK1. 2 / 2

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