IndraLab

Statements

Alzheimer Disease activates UCHL1. 2 / 2
| 2
reach
"These and other lines of evidence support a role for dysfunction of the ubiquitin-proteosome pathway in the pathogenesis of AD supporting the importance of the UCH-L1 protein."
20384815
reach
"Moreover, overexpression of UCHL1 delays AD progression in mouse models, and UCHL1 gene therapy, to overexpress UCHL1, in the brain potentially could be a promising disease modifying strategy for AD therapeutics."
26881020