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Hypoxia decreases the amount of USP19. 3 / 3
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"Hence, pioneering researches rarely focused on whether and how hypoxia regulates the Beclin-1 expression in cervical cancer.In this study, we found that hypoxia will induce significant decrease of bot[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Our findings revealed that the hypoxia treatment could obviously decrease the USP19 expression ( Fig. 2 A and B )."

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"Hypoxia not only diminishes Beclin-1 and USP19 levels but also triggers a dual suppression mechanism through a coherent feed-forward loop."