IndraLab

Statements

USP3 activates Neoplasm Metastasis. 9 / 9
| 3 6
eidos
"These data suggest that USP3 promotes GC progression and metastasis by deubiquitinating COL9A3 and COL6A5 ."
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"Here, we report that ubiquitin specific peptidase 3 (USP3) promotes proliferation and metastasis of esophageal squamous cell carcinoma (ESCC) cells by mediating deubiquitination of Aurora A. Analysis of human clinical samples indicated that USP3 and Aurora A are highly expressed in ESCC."
34758762
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"Silencing of USP3 suppressed GC cell proliferation and spreading in vitro as well as xenograft proliferation and metastasis in vivo; however, opposite results were obtained when USP3 was overexpressed."
30168892
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"USP3 knockdown induced metastasis was abolished by USP3 3 ' UTR overexpression in CRC cells."
28655924
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"Hsa_circ_0017639 expression promotes gastric cancer proliferation and metastasis by sponging miR-224-5p and upregulating USP3 ."
32376451
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"USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3 / COL6A5 stabilisation ."
34930901
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"USP3 promotes gastric cancer progression and metastasis by deubiquitination-dependent COL9A3/COL6A5 stabilisation."
34930901
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"However, the mechanism by which USP3 promotes gastric cancer (GC) metastasis remains largely unknown."
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"Protein deubiquitylase USP3 stabilizes Aurora A to promote proliferation and metastasis of esophageal squamous cell carcinoma."
34758762