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KCNQ1-S140G activates sensor. 2 / 2

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"We show that KCNQ1 S140G directly slows voltage sensor deactivation which in turn slows current deactivation, whereas KCNQ1 V141M has minimal effect on channel gating."

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"Taken together, these experiments show that KCNQ1 S140G slows voltage sensor deactivation even in the absence of channel opening."

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IndraLab

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KCNQ1-S140G activates sensor. 2 / 2

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