IndraLab

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USP2 deubiquitinates KRAS. 2 / 2
| 2

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"Taken together, these results suggest that USP2 may enhance the protein stability of KRAS.Based on the above results, we hypothesized that USP2 may interact with and deubiquitinate KRAS."

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"To determine whether USP2 deubiquitinates KRAS, USP2 , USP2 and its active-site mutant, USP2 , were separately transfected into HEK293T cells, which were subsequently lysed and subjected to the immunoprecipitation assay."