IndraLab

Statements

CACNA1E inhibits autophagy. 2 / 2
| 2
reach
"The LC3A and B-II expression levels, which drastically inhibited by rTF, rFVII or PAR2 activation, were fully rescued by mTOR knockdown in vitro, suggesting mTOR signaling pathway could have a key role in tumor malignancy through TF/FVII/PAR2 mediated suppression of autophagy."
24853422
reach
"The levels of the autophagic cargo receptor p62 (SQSTM1) in protein lysates from P3 cells after TMZ treatment were minimally altered relative to untreated controls, whereas the level of the autophagy marker LC3A/B-II was diminished by approximately 40% (Figure 2A), potentially indicating sustained autophagy."
36619857