IndraLab

Statements

USP27X deubiquitinates CGAS. 3 / 3
| 3
reach
"Cutting Edge : USP27X Deubiquitinates and Stabilizes the DNA Sensor cGAS to Regulate Cytosolic DNA Mediated Signaling."
31534008
reach
"USP27X and USP29 have a similar mechanism for the deubiquitination of cGAS, both preventing the degradation of cGAS via the proteasomal pathway by removing the K48-linked ubiquitin chain of cGAS and maintaining cGAS protein levels."
36579404
reach
"Guo et al. have reported that cGAS can be deubiquitinated by USP27X, thereby promoting the stability of cGAS protein and increasing cGAMP expression [22] ."
37478666