IndraLab

Statements


3 | 2 4

sparser
"In breast cancer, Yingying Wu et al. found that the carboxyl-terminal active region of USP3 (residues 111–521aa) binds to the amino-terminal region of KLF5 (residues 1–200aa) to promote KLF5 expression via deubiquitination ( xref )."

reach
"USP3 can interact with KLF5 and stabilize KLF5 through deubiquitination."

No evidence text available

No evidence text available

No evidence text available

reach
"We demonstrated that USP3 interacts with KLF5 and stabilizes KLF5 via deubiquitination."

sparser
"We demonstrated that USP3 interacts with KLF5 and stabilizes KLF5 via deubiquitination."

sparser
"Notably, unlike USP3, the active region of USP38 is located at the amino terminus (1-400aa), indicating that although both USP38 and USP3 bind to the same active region of KLF5, the differences in their respective active regions may lead to differential sensitivity in regulating KLF5 expression."

sparser
"USP3 can interact with KLF5 and stabilize KLF5 through deubiquitination."