IndraLab

Statements


MYSM1 increases the amount of PAX5. 2 / 2
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"Further, we tested the possibility that MYSM1 may directly activate the transcription of Pax5 in mature B cells as well."

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"Mechanistic studies revealed that MYSM1 activates Pax5 transcription by coordinating histone modifications and directing the recruitment of the transcription activators such as PU.1 to the Pax5 locus in B cells."