IndraLab

Statements

KCNH2 inhibits moxifloxacin. 2 / 2
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"The mechanistic consistency observed across species for a given drug greatly enhances the confidence in using these preclinical models as prospective indicators of effects in human subjects.The hERG b[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Compared to PSS, the IC 50 values, conducted at room temperature, of the classic hERG blocking drugs cisapride, moxifloxacin, and terfenadine were shifted to the right by an extent predicted by their known plasma protein binding, but we did not detect any differences in IC 50 s between male and female serum."
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