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OTUB1 leads to the deubiquitination of AKT on K63. 2 / 2
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"Otub1 inhibits K63 ubiquitination and PIP3-binding function of AKT."

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"Moreover, OTUB1 is found to inhibit K63-linked ubiquitination and the PIP3-binding function of AKT in a manner dependent on the catalytic residues Cys91 and Asp88, thereby decreasing AKT phosphorylati[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"