IndraLab

Statements


USP7 activates CDKN1A. 3 / 3
| 3

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"Additionally, we also observed among different patient groups that the USP7 / p300 / p53 / p21 proteins were highly expressed in EPCs in smoking COPD patients in comparison with the others, indicating[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"Next we tested whether USP7 enhanced p53 function by examining the induction of p21 in H1299 cells after transfection of a p53 expressing plasmid alone or in combination with a plasmid expressing either WT USP7 or a USP7 mutant (XREF_FIG)."

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"Consistent with the ChIP results, coexpression of WT USP7 or C223S led to induction of p21 (lanes 3 and 4)."