IndraLab

Statements


BAP1 activates CDKN. 1 / 1
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"Within the melanoma dominant syndromes caused by cyclin dependent kinase inhibitor 2A (CDKN2A), and BRCA1 associated protein 1 (BAP1), pathogenic mutations in these genes cause increased incidence of other cancer types (e.g., pancreatic cancer, neurological tumors, renal cell carcinoma, mesothelioma) but with lower penetrance than melanoma [XREF_BIBR]."