IndraLab

Statements

FBXO32 activates EIF3F. 7 / 7
| 7
reach
"Of note, a subset of microRNAs (miRNAs) in the delta like homolog 1 and the type III iodothyronine deiodinase (Dlk1-Dio3) cluster showed an anti-atrophic effect, probably by limiting the degradation of eIF3f by MAFbx and atrogin -1 [XREF_BIBR]."
| PMC
reach
"MAFbx has been shown to target and degrade MyoD, myogenin, and Eif3f, and degradation of any of these proteins reduces myotube diameters."
23523565
reach
"Ectopic expression of MAFbx in myotubes induces atrophy and degradation of eIF3-f."
18354498
reach
"MAFbx has been shown to target and degrade MyoD, myogenin, and Eif3f (Csibi et al., 2009; Jogo et al., 2009; Lagirand-Cantaloube et al., 2008; Tintignac et al., 2005), and degradation of any of these [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
23523565
reach
"Muscles undergoing atrophy accumulates the inactive form of S6K1 suggesting that degradation of eIF3f mediated by MAFbx participates to S6K1 inactivation during atrophy and raises the question whether MAFbx interacts with free eIF3f molecules or bound to hypophosphorylated S6K1."
20126553
reach
"It was found that the E3 ubiquitin ligase MAFbx and atrogin -1 targets the Mov34 motif of eIF3f during atrophy for polyubiquitination and subsequent degradation by the proteasome [XREF_BIBR, XREF_BIBR, XREF_BIBR]."
| PMC
reach
"Atrogin-1 also targets myogenic differentiastion1 (MyoD) and eukaryotic initiation factor 3 subunit 5 (eIF3-f), which play key roles in the control of protein synthesis XREF_BIBR."
25032690