IndraLab

Statements


USP18 activates MYC. 3 / 3
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"To further validate that USP18 mediated the growth of PC cells by regulating c-Myc, we first increased the expression of c-Myc in USP18 knockdown PC cells and then measured the USP18 and c-Myc protein expression levels and cell proliferation."

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"USP18 null leiomyosarcoma cell lines are aneuploid and overexpress MYC."

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"Collectively, these data strongly suggested that USP18 positively regulates c-Myc in PC."