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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP18 activates MYC. 3 / 3

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"To further validate that USP18 mediated the growth of PC cells by regulating c-Myc, we first increased the expression of c-Myc in USP18 knockdown PC cells and then measured the USP18 and c-Myc protein expression levels and cell proliferation."

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"USP18 null leiomyosarcoma cell lines are aneuploid and overexpress MYC."

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"Collectively, these data strongly suggested that USP18 positively regulates c-Myc in PC."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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USP18 activates MYC. 3 / 3

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