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"32 In lung cancer cells, UCHL1 promoted PD-L1 expression and inhibition of UCHL1 might suppress immune escape of NSCLC through downregulation of PD-L1 expression in NSCLC cells.33 Therefore, based on the previous studies on UCHL1 as well as the findings of our group, it is suggested by the results of the present study for the first time that UCHL1 may act as an important mechanistic factor in radiotherapy combined with immunotherapy in patients with cervical cancer.It is well established that GnRH1 and its receptor are expressed in cancer cells derived from reproductive tissues and administration of GnRH1 analogs inhibits their proliferation.34,35 Our study shows for the first time that the differential expression of GNRH1, a prognostic gene, in CC cervical cancer patients is regulated by ferroptosis and immunity."