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USP10 inhibits EIF4G1. 2 / 2
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"The results showed that CHX treatment reduced the protein level of EIF4G1, but USP10 knockdown increased the degradation rate of EIF4G1 in H1299 cells (Fig. 2A)."
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"Using tandem affinity purification combined with mass spectrometry (TAP-MS) screening approach, we have identified that ubiquitin specific protease 10 (USP10) can directly interact with EIF4G1 and inhibit EIF4G1 activities in NSCLC cells [XREF_BIBR], although the underlying mechanism remains largely unknown and further investigations are warrant to solve this puzzle."
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