Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

COPS5 decreases the amount of CD274. 2 / 2

| 2

➶

reach

"Downregulation of CSN5 reduced TNF-alpha-induced PD-L1 expression (XREF_FIG), indicating that CSN5 is required for PD-L1 stabilization."

27866850

➶

reach

"Half-life analysis using cycloheximide pulse-chase analysis indicated that downregulation of CSN5, but not CSN2, which has been shown to destabilize Snail, reduced PD-L1 expression as well as its protein half-life (XREF_FIG)."

27866850

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...