IndraLab

Statements


COPS5 decreases the amount of CD274. 2 / 2
| 2

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"Downregulation of CSN5 reduced TNF-alpha-induced PD-L1 expression (XREF_FIG), indicating that CSN5 is required for PD-L1 stabilization."

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"Half-life analysis using cycloheximide pulse-chase analysis indicated that downregulation of CSN5, but not CSN2, which has been shown to destabilize Snail, reduced PD-L1 expression as well as its protein half-life (XREF_FIG)."