IndraLab

Statements

KCNMA1 activates LSM1B. 3 / 3
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"In addition, TBI‐mediated increased endothelial NO production acts through sGC, PKG, and SM BK channel activation to cause vasodilation and ablation of myogenic tone."
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sparser
"Several downstream targets have been proposed to contribute to sGC/PKG‐dependent vasodilation, including SM BK channel activation. xref – xref In cerebral arteries from control animals, vasodilation evoked by spermine NONOate was reduced by BK channel blockade with paxilline (1 μmol/L) ( xref B), consistent with NO activation of BK channels."
25527626
sparser
"11,12-epoxyeicosatrienoic acid (11,12-EET), an endothelium-derived hyperpolarizing factor, dilates human internal mammary arteries through SM BK channel activation [ xref ]."
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