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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

HCN1 activates Trp-Ala-Gly. 2 / 2

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"The basis of thalamic HCN1 upregulation in GAERS and WAG and Rij rats is unclear : Genomic analyses have not revealed mutations of the HCN1 gene so that a developmental dysregulation due to abnormalities in the thalamic network is plausible."

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"Importantly, altered expression of HCN1 channels in TC neurons and cortical pyramidal neurons was found to underlie the SWD phenotype of WAG and Rij and GAERS rats."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...