IndraLab

Statements

CYLD activates Neoplasm Metastasis. 5 / 5
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"Hayashi et al. have found that CYLD downregulation promoted breast cancer metastasis via NF-kappaB activation, including RANKL signaling [XREF_BIBR]."
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"Moreover, CYLD has also been reported to promote melanoma tumorigenesis and metastasis through suppression of JNK and activating protein 1 (AP-1), leading to decreased expression of cyclin D1 and N-cadherin XREF_BIBR."
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"CYLD downregulation may promote breast cancer metastasis via NF-kappaB activation, including RANKL signaling."
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"It has been recently suggested that CYLD down-regulation could increase breast cancer metastasis through NFkappaB activation."
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"In conclusion, PCDH-gamma-A12 and SLC19A1 promoters, but not CREB and CYLD promoters, are hypermethylated and contribute to the occurrence and metastasis of colorectal cancer."
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