IndraLab

Statements


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sparser
"Here, we report cryoelectron microscopy structures of the human KCNQ5-calmodulin (CaM) complex in the apo, PIP 2 -bound, and both PIP 2 - and the activator HN37-bound states in either a closed or an open conformation."

sparser
"The distribution pattern of the voltage-dependent potassium channel KCNQ5 in the rat retina and the changes that took place during photoreceptors loss, which are shown in this study, support the hypot[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"We herein demonstrate that CaM also interacts with KCNQ5 in the rat retina and that this interaction can act as a marker during the retinal degeneration process."

sparser
"Based not only on these observations, but also on arguments in other studies ( Gamper et al., 2005; Yus-Najera et al., 2002 ), we propose a correlation between the retinal degeneration progress and th[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"Intracellular Ca 2+ recordings of glial cells were carried out in the NFL of the retinas at P100 when the KCNQ5/CaM interaction was at its greatest."

reach
"Although the KCNQ5/CaM interaction increased as a result of age in the SD retinas, it was significantly higher in the P23H-1 rats during retinal degeneration."

reach
"Based not only on these observations, but also on arguments in other studies ( Gamper et al., 2005; Yus-Najera et al., 2002 ), we propose a correlation between the retinal degeneration progress and th[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

reach
"If the effect of the KCNQ5/CaM interaction on the retina was similar to that in CHO cells and yeast, we can assume that the open probability of the potassium channels in the inner retina lowered and, [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"