IndraLab

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Lapatinib inhibits MAPK8. 2 / 2

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"JNK1 knockdown, and to a lesser extent compound JNK1 and JNK2 knockdown, significantly rescued cell viability when treated with JNK-IN-8 and lapatinib combination."

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"In addition , lapatinib successfully prevented activation of the EGFR-RAF-MEK1 / 2-ERK1 / 2 pathway in Jnk1 / 2 mice ."

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IndraLab

Statements

Lapatinib inhibits MAPK8. 2 / 2

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