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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP2 inhibits NEDD4L. 2 / 2

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"The biochemical experiments show an augmented surface expression and reduced ubiquitylation level of KCNQ1 when catalytically active USP2 is coexpressed with Nedd4-2, suggesting that USP2 may counter [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In cells coexpressing USP2-45/-69, the amount of ubiquitylated KCNQ1 was significantly decreased and the total amount of KCNQ1 was increased, demonstrating that USP2 antagonizes the effect of Nedd4-2 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...