IndraLab

Statements


ZRANB1-C443A activates IL12B. 2 / 2
| 2

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"In similar experiments using BMDCs, reconstitution of DC-cKO BMDCs with wild-type Trabid, but not C443A Trabid, rescued the induction of Il12a, Il12b, and Il23a genes (XREF_FIG)."

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"Consistently, reconstitution of KO MEFs with wild-type Trabid, but not C443A Trabid, greatly promoted poly (I : C)-induced Il12b, Il12a and Il23a mRNA expression in these cells (XREF_FIG) but had no effect on the induction of the control gene Il6 (XREF_FIG)."