IndraLab

Statements

GLI1 increases the amount of USP25. 3 / 3
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"Importantly, we go on to show that either depletion or overexpression of USP21 suppresses Gli1 dependent transcription in human cells."
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"Intriguingly, overexpression of USP21 represses Gli1 dependent transcription, despite the fact that the total amount of Gli1 is clearly increased."
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"Importantly, we show that both depletion and overexpression of catalytically active USP21 suppress Gli1 dependent transcription."
27621083