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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

GLI1 increases the amount of USP25. 3 / 3

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"Importantly, we go on to show that either depletion or overexpression of USP21 suppresses Gli1 dependent transcription in human cells."

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"Intriguingly, overexpression of USP21 represses Gli1 dependent transcription, despite the fact that the total amount of Gli1 is clearly increased."

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"Importantly, we show that both depletion and overexpression of catalytically active USP21 suppress Gli1 dependent transcription."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

GLI1 increases the amount of USP25. 3 / 3

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