IndraLab

Statements


CD274 increases the amount of CD44. 2 / 2
| 2

reach
"Recently, Lotfinejad et al. have shown that inhibiting tumoral PD-L1 can substantially decrease CD44 expression in TNBC cells (37)."

reach
"Mechanistically, CD44 activated PD-L1 transcription in part through its cleaved intracytoplasmic domain (ICD), which bound to a regulatory region of the PD-L1 locus containing a consensus CD44-ICD binding site."