IndraLab

Statements


CACNA1A activates CD62L-. 2 / 2
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"B/I selectively activates CD62L- T cells, which represent the " sensitized " T cells capable of anti-tumor activity and is unique to B/I activation compared to anti-CD3 activation [XREF_BIBR, XREF_BIBR]."

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"In the 4T1 mammary carcinoma model, we have previously shown that B/I selectively activates CD62L- or sensitized T cells and that the anti-tumor activity resides in the CD62L- fraction of lymphocytes obtained from donor lymph nodes; only the CD62L- subset proliferates after B/I activation and has anti-tumor activity [XREF_BIBR]."