IndraLab

Statements


UCHL1 inhibits TP53. 3 / 3
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"Moreover, Li et al. showed that UCHL1 promotes tumor suppressor p53 signaling and is silenced due to its promotion of methylation in nasopharyngeal carcinoma [64]."

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"Interestingly, UCHL1 promotes p53 signaling in nasopharyngeal carcinoma 40 and PADI2 facilitates p53 degradation in breast cancer cells."

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"It is also possible that UCH-L1 indirectly elicits control over p53 by modulating negative regulators of p53, such as mdm2, as suggested by Li et al. [XREF_BIBR]."