IndraLab

Statements

OTUD7B activates UIMC1. 2 / 2
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reach
"Whereas the UBA domain by itself does not rescue RAP80, Abraxas, and BRCA1 IRIF, a truncated N terminus of Cezanne that contains both the UBA domain and the DUB domain (UBA-OTU), but not a DUB inactivated version (UBA-OUT*), rescues the phenotype (Fig. 3B)."
31699778
reach
"The different roles of Cezanne and Cezanne2 in promoting Rap80 or Rad18 and 53BP1 suggest that the K63-dependent recruitments of DNA repair proteins are differentially regulated by Cezanne and Cezanne2."
31699778