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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TNFAIP3 inhibits IKBKB. 3 / 3

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"Also, TNFAIP3 acts to deactivate IKK1 and IKK2."

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"TNF alpha induced protein 3 (A20, also known as TNFAIP3) is also induced upon NF-kappaB activation and negatively regulates IKKbeta activity."

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"A20, a deubiquitinating enzyme, inactivates IKKβ by removing regulatory K63-linked polyubiquitin chains from IKKγ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...