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Sensor activates KCNH2. 2 / 2
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"Using several mutations as tools, we define key steps in the deactivation pathway that limit voltage sensor return to produce the physiologically relevant resurgent hERG current in cardiomyocytes.Wild[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"The fourth transmembrane segment (S4) contributes to form the voltage sensor domain (VSD), which sharply contributes to hERG1 biophysical properties [XREF_BIBR]."