IndraLab

Statements

OTUB1 is phosphorylated on S16. 4 / 4
| 4
rlimsp
"Phosphorylation of OTUB1 on Ser16 has been implicated in nuclear targeting43."
27080861
rlimsp
"Whereas we detected unphosphorylated OTUB1 mainly in the cytosol, we detected Ser(16)-phosphorylated OTUB1 only in the nucleus."
25872870
rlimsp
"Pharmacological inhibition or genetic ablation of CK2 blocked the phosphorylation of OTUB1 at Ser(16), causing its nuclear exclusion in various cell types."
25872870
rlimsp
"In vitro, Ser(16)-phosphorylated OTUB1 and nonphosphorylated OTUB1 exhibited similar catalytic activity, bound K63-linked ubiquitin chains, and interacted with the E2 enzyme UBE2N."
25872870