IndraLab

Statements

CCNB1 binds USP22. 12 / 17
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"Our studies suggest that SIRT1 and CCNB1 interact with USP22 through different regions."
27030811
sparser
"However, this report clearly demonstrates that USP22 binds and deubiquitinates cyclin B1, leading to its stabilization."
32201366
sparser
"USP22 binding to Cyclin B1, promotes cyclin B1 accumulation in the nucleus and inhibits its degradation [ xref ]."
27057639
sparser
"USP22 interacts with CCNB1."
27030811
sparser
"The interaction between endogenous USP22 and CCNB1 in human colon cancer cells was also detected, as anti-CCNB1-specific antibody but not normal mouse immunoglobulin G immunoprecipitated USP22 protein ( xref )."
27030811
sparser
"To further refine our understanding of the molecular interaction between USP22 and CCNB1, we generated truncated USP22 mutants ( xref )."
27030811
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"USP22 binding to Cyclin B1, promotes cyclin B1 accumulation in the nucleus and inhibits its degradation [XREF_BIBR]."
27057639
sparser
"In addition, as S237 is also within the portion of USP22 that interacts with CCNB1, it is possible that CDK1-mediated S237 phosphorylation enhances USP22 interaction with CCNB1."
27030811
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"USP22 interacts with CCNB1."
27030811
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"The interaction between endogenous USP22 and CCNB1 in human colon cancer cells was also detected, as anti-CCNB1-specific antibody but not normal mouse immunoglobulin G immunoprecipitated USP22 protein (XREF_FIG)."
27030811
reach
"To further refine our understanding of the molecular interaction between USP22 and CCNB1, we generated truncated USP22 mutants (XREF_FIG)."
27030811
sparser
"USP22 can interact with cyclin B1, promoting its deubiquitination and stabilization."
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