IndraLab

Statements


Kinase-active AKT1 phosphorylates MTOR. 2 / 2
2 |

"The mammalian target of rapamycin (mTOR), a 290 kDa serine/threonine kinase and aminoacid sensor, is a direct target for Akt [33]."

"once Akt1 is activated, it initiates a cascade of phosphorylation events targeting mammalian target of rapamycin, mTOR, which in turn phosphorylates the p70S6 kinase and GSK3B"