IndraLab

Statements

COPS5 activates E3_Ub_ligase. 4 / 4
| 4
reach
"1,7,12 Therefore, it can be speculated that JAB1 promotes TRAF2 E3 ligase activity through the action of one of its associated kinases, which have not been identified in this study ( Figure 8 )."
16936264
reach
"In turn, the protected Jab1 activity can prevent the degradation of Cullin RING E3 ligases by the Ub/Ub like dependent degradation pathways."
32456285
reach
"These results suggest that the effects of JAB1 on ubiquitination of RIP1 are mediated through the effects of JAB1 on TRAF2 E3 ligase activity, and that JAB1 results in an enhancement of this activity.[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
16936264
reach
"CSN5 and Jab1 deconjugates the Ub like modifier Nedd8 to modulate the activity of the SCF E3 ligase [XREF_BIBR]."
23845989