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USP13 increases the amount of BECN1. 2 / 2

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"Similarly, the overexpression of USP13 reduced the levels of ubiquitinated Beclin1 which was inhibited by spautin-1 (Figure 4E)"

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"Moreover, beclin-1 and USP10 are involved in a potential feedforward mechanism in which beclin-1 stabilizes USP13, which in turn deubiquitinates and stabilizes USP10, leading to increased beclin-1 levels and activity."

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IndraLab

Statements

USP13 increases the amount of BECN1. 2 / 2

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