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USP7 inhibits cellular senescence. 2 / 2

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"In contrast, knockdown of USP7 with two independent shRNAs caused senescence in both the Leiden and control fibroblasts."

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"We show that USP7 downregulation induces cellular senescence , arresting melanoma growth in vivo and proliferation in vitro in BRAF - and NRAS-mutant melanoma ."

36130505

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IndraLab

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USP7 inhibits cellular senescence. 2 / 2

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