IndraLab

Statements


USP15 inhibits RNF26. 2 / 2
| 2

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"Furthermore, expression of wild-type (but not inactive) USP15 reduced the degree of colocalization of RNF26 with SQSTM1 (XREF_FIG C, 6D, and XREF_FIG B), indicating that USP15 activity modulates occupancy of ligase positive sites."

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"However, RNF26 effects on LE positioning can be reversed by USP15, allowing LE movement along microtubules."