IndraLab

Statements

TAB1 binds USP18. 7 / 8
2 | 4 1
reach
"In overexpression and co-immunoprecipitation assays, USP18 interacted with TAB1 and CARMA1 but not with NEMO constitutively (XREF_FIG and not depicted)."
23825189
sparser
"We also found that USP18 weakly interacts with TAB1 alone ( xref ), but it has higher affinity for the TAK1-TAB1 complex in the presence of TAK1 ( xref )."
26240016
biogrid
No evidence text available
23825189
reach
"The results indicated that USP18 interacted with TAK1, TAB1, and TAB2 without stimulation and PMA and ion stimulation reduced but did not totally abolish their association, whereas USP18 interacted with CARMA1 weakly in unstimulated cells and PMA and ion stimulation first enhanced their interaction and then resulted in their disassociation (XREF_FIG)."
23825189
reach
"We also found that USP18 weakly interacts with TAB1 alone (XREF_FIG), but it has higher affinity for the TAK1 and TAB1 complex in the presence of TAK1 (XREF_FIG)."
26240016
reach
"However, USP18 binds to TAB1 and inhibits the ubiquitination of the TAB1 and TAK1 complex."
23825189
biogrid
No evidence text available
26240016